Thanks manhta
That helped narrow the issue... As I personally checked the php.ini file over and over again.
However, wasn't able prior to your final message to locate.
Until I noticed our primary php.ini
; Relative path can also be used. They will be prefixed by:
; - the global prefix if it's been set (-p argument)
; - /usr otherwise
include=/etc/php/8.0/fpm/pool.d/*.conf
So there was a "hidden" conf file that is specific to each site in the pool.d conf.
And boom we located the disabled_function that contained the tmpfile.
Removed and everything works great..
Thanks for all of your help...
We are good and can close this ticket.