Can’t think why you would want to take the engine out of an F1 car but each to their own!
I have tried this on an Elastica so I have no idea if it will be the same for Puresite. I don’t know the layout of Puresite.
*You do this at your own risk.
One way I found to do it was to go into Template Manager, Elastica, Layouts. I cloned the default and then deleted this line from it
<file>js/jquery.masonry.js</file>
saved it and then assigned this layout for the desktop and it seemed to work. It may not do so for you but of course you could also look at the developers site and use the ‘destroy’ or ‘remove’ functions as he describes – http://masonry.desandro.com/docs/methods.html
You could always start with a T3 blank and go from there and build your own template! Or let your users experience Puresite as she was meant to be! :p